

To The Best Of Our Knowledge
Wisconsin Public Radio
”To the Best of Our Knowledge” is a Peabody award-winning national public radio show that explores big ideas and beautiful questions. Deep interviews with philosophers, writers, artists, scientists, historians, and others help listeners find new sources of meaning, purpose, and wonder in daily life. Whether it’s about bees, poetry, skin, or psychedelics, every episode is an intimate, sound-rich journey into open-minded, open-hearted conversations. Warm and engaging, TTBOOK helps listeners feel less alone and more connected – to our common humanity and to the world we share.For more from the TTBOOK team, visit us at ttbook.org.
Episodes
Mentioned books

Jul 9, 2022 • 52min
Decolonizing the Mind
Colonization in Africa was much more than a land grab. It was a project to replace — and even erase — local cultures. To label them inferior. Music, arts, literature and of course language. In other words, it permeated everything. So how do you undo that? How do you unlearn what you’ve been forced to learn?
In this hour, produced in partnership with the Consortium of Humanities Centers and Institutes (CHCI) and Africa is a Country — we learn what it means to decolonize the mind.
Original Air Date: March 20, 2021
Guests:
Adom Getachew — Simon Gikandi — Ngugi wa Thiong’o
Interviews In This Hour:
Reckon with the Past To Decolonize the Future — Reclaiming the Hidden History of Blackness — Never Write In The Language of the Colonizer
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Jul 2, 2022 • 52min
Are you ready for the psychedelic revolution?
The psychedelic revolution in mental health treatment is on the way, with FDA approval likely in just a few years. Which means that before long, the treatment of choice for depression and addiction could be a hallucinogen like psilocybin. And more psychedelic compounds are in the pipeline for PTSD and other disorders.
Original Air Date: July 02, 2022
Guests:
Alex Sherwood — Bill Linton — Lou Lukas
Interviews In This Hour:
The lab that could supply psilocybin to the world — Psilocybin, the 'God molecule,' and the quest to revolutionize mental health care — Could psychedelics erase our fear of dying?
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Jun 25, 2022 • 52min
Shapeshifting
There are old folktales and legends of people who can become animals. Animals who can become people. And there’s a lesson for our own time in those shapeshifting stories — a recognition that the membrane between what's human and more-than-human is razor thin.
Human identity cannot be separated from our nonhuman kin. From forest ecology to the human microbiome, emerging research suggests that being human is a complicated journey made possible only by the good graces of our many companions. In partnership with the Center for Humans and Nature and with support from the Kalliopeia Foundation, To The Best Of Our Knowledge is exploring this theme of "kinship" in a special radio series.
To learn more about the Kinship series, head to ttbook.org/kinship.
Original Air Date: November 20, 2021
Guests:
Sharon Blackie — David Abram — Chris Gosden — Stephen Graham Jones
Interviews In This Hour:
Reclaiming the fierce women who are shapeshifters — How a man turned into a raven — Shapeshifters, shamans and the 'New Animism' — Horror author Stephen Graham Jones on what our monsters say about us
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Jun 18, 2022 • 52min
You're Not Ok. That's Ok.
At the height of the COVID-19 pandemic, producer Charles Monroe-Kane made 300 yard signs that read "You're not ok. That's ok." He put them on his porch. Soon they were gone.
Original Air Date: June 18, 2022
Guests:
Charles Monroe-Kane — Susan Cain — Alissa Wilkinson — Mary Laura Philpott
Interviews In This Hour:
The story of a pandemic yard sign — Author Susan Cain on how bittersweetness adds flavor to daily life — 'Artists anticipate things because they work in the realm of the imagination': Creating in a pandemic time loop — What would you put in your bomb shelter?
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Categories: depression, mental health, COVID-19, pandemic

Jun 11, 2022 • 52min
Mysteries of Migration
If you had to travel 500 miles across country, on foot, with no map, no GPS, without talking to anyone — to a destination you've never seen, could you do it? It sounds impossible, but millions of creatures spend their lives on the move, migrating from one part of the Earth to another with navigation skills we can only dream of. How do they do it — and what can we learn from them?
Original Air Date: July 25, 2020
Guests:
Moses Augustino Kumburu — David Wilcove — Stan Temple — David Barrie — Sonia Shah
Interviews In This Hour:
The Serengeti's Great Migration, Up Close — Why Do Animals Migrate? — Sandhill Cranes Make The Long Journey South — The Greatest Navigators on the Planet — The High Costs — And Potential Gains — Of Migration, Both Animal And Human
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Jun 4, 2022 • 52min
As Read By The Author
As audio producers, one of the most fun things we get to do is bring the soundscape of a novel to life — cue the monsters, the storms, the footsteps of a creature emerging slowly from the ocean. So that’s what we’re bringing you today: Great writers, epic sound design.
Original Air Date: July 03, 2021
Guests:
Nnedi Okorafor — Neil Gaiman — N. K. Jemisin — Ann Patchett — Richard Powers — Lorrie Moore — Kelly Link — Mark Sundeen
Interviews In This Hour:
Nnedi Okorafor's Alien Invasion of Lagos — Neil Gaiman Brings Us To The End Of The World — A Not So Distant Future in the N.K. Jemisin's 'Broken Earth' Trilogy — Ann Patchett on 'State of Wonder' — Richard Powers on Writing the Inner Life of Trees — Lorrie Moore on Bringing Characters To Life With Brevity — Kelly Link on 'Pretty Monsters' — Mark Sundeen on 'The Making of Toro'
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May 28, 2022 • 52min
The Hidden Geometry of Everything
The human brain is naturally mathematical. But there’s one particular kind of math people have surprisingly strong feelings about — geometry. It's the secret sauce of mathematics — different from everything else, and applicable to everything from gerrymandering to human evolution to romance novels.
Original Air Date: May 28, 2022
Guests:
Jordan Ellenberg — Stanislas Dehaene
Interviews In This Hour:
The 14th dimension, AI that writes romance novels, and other things explained by geometry — Did shapes make us human?
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May 21, 2022 • 52min
Living With Loneliness
After a pandemic year of social isolation, we knew loneliness would be a problem. But public health officials have been warning for years that in countries all over the world, rates of loneliness are skyrocketing. How did loneliness become a condition of modern life?
Original Air Date: April 10, 2021
Guests:
Jason Rohrer — Samantha Rose Hill — Claudia Rankine
Interviews In This Hour:
My Friend Samantha (The A.I.) — How Loneliness Can Lead to Totalitarianism — Being Black and Alone in America
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May 14, 2022 • 52min
How To Be An Ethical Traveler
Before the pandemic upended all world travel, we aired a show about what it means to be an ethical traveler. Between masks and vaccinations, COVID-19 has added even more to the ethical baggage we carry with us when we travel. But part of recovering from the pandemic involves getting back out there and seeing the world.
So before you take your next trip abroad, we thought we would revisit some thoughts and advice in that episode. Safe journeys.
This show was produced in partnership with AFAR Magazine, whose May/June 2019 issue on ethical traveling inspired this episode.
Original Air Date: May 25, 2019
Guests:
Elizabeth Becker — Dave Eggers — Kathryn Kellogg — Anu Taranath — Barry Lopez
Interviews In This Hour:
Trying Not To Ruin The World By Visiting It — A Personal Code of Travel Ethics — How to Lessen Your Environmental Impact When You Travel — Traveling Abroad Without Falling Into Guilt Trips — To Travel Well, Be Willing To Listen, Play, Leave The Notebook Behind
Further Reading:
Afar Magazine: Making the World Better, One Traveler at a Time—Afar Magazine: 4 Ways to Explore Venice Responsibly—Afar Magazine: Are We Loving Venice to Death?—Afar Magazine: How to Photograph People When You Travel (Without Being Disrespectful)
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May 7, 2022 • 52min
Writing As A Political Act
In peaceful times, and in moments of violence, writers have used their art as protest, remembrance, and sometimes, political acts. We talk with poets and novelists about how they deeply notice the historical time we live in — through their words and voice.
Original Air Date: May 07, 2022
Guests:
Ilya Kaminsky — Bernardine Evaristo — Christopher Benfey — Salman Rushdie
Interviews In This Hour:
Poetry as protest: 'When people are powerless for so many hundreds of years, language becomes a weapon' — 'All writing is political': Author Bernardine Evaristo on tenacity, growing up Black and British, and winning the Booker Prize — Should we still read the 'proud imperialist' Kipling?
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