
To The Best Of Our Knowledge
”To the Best of Our Knowledge” is a Peabody award-winning national public radio show that explores big ideas and beautiful questions. Deep interviews with philosophers, writers, artists, scientists, historians, and others help listeners find new sources of meaning, purpose, and wonder in daily life. Whether it’s about bees, poetry, skin, or psychedelics, every episode is an intimate, sound-rich journey into open-minded, open-hearted conversations. Warm and engaging, TTBOOK helps listeners feel less alone and more connected – to our common humanity and to the world we share.
For more from the TTBOOK team, visit us at ttbook.org.
Latest episodes

Apr 19, 2025 • 52min
On Pilgrimage with Dorothy Day
How does someone become an official saint? Meet Dorothy Day — journalist, radical activist, mother and lay minister to the poor who died in 1980 — who is being considered for sainthood by the Catholic Church. Shannon Henry Kleiber walks in her footsteps through New York City, where she lived and worked, looking for miracles, talking with people whose lives were changed by her, and wondering how and why saints matter today.We are grateful for additional music for this show from Tom Chapin, Si Kahn and the Chapin Sisters. Thanks also to the Dorothy Day Guild, and The Department of Special Collections and University Archives, Marquette University Archives, which houses Dorothy Day’s papers and photos.Original Air Date: April 19, 2025Interviews In This Hour: In search of miracles, favors and graces — Inside the ‘agony and ecstasy’ of Maryhouse — We are all ‘called to be saints’Guests: Robert Ellsberg, Martha Hennessy, Fr. James MartinNever want to miss an episode? Subscribe to the podcast.Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.

Apr 12, 2025 • 52min
Off The Map
Lagipoiva Cherelle Jackson, a Samoan journalist, shares her poignant experiences documenting climate change's impact on Pacific islands. Bill Limpisathian, a cartography professor, explains how our brains interact with maps and the shift from paper to digital navigation. Uzbekistani electronic musician Andrew Pekler introduces his innovative project featuring a sonic atlas of phantom islands, blending music with geography. Together, they discuss the cultural, emotional, and cognitive dimensions of mapping in the face of environmental challenges.

Apr 5, 2025 • 52min
Welcome to the Island of Knowledge
Peter Tse, a Dartmouth neuroscientist, discusses the unique role of human imagination as both a gift and a potential threat. Marcelo Gleiser, an astrobiologist, shares insights on the Big Bang and emphasizes humanity's urgent need to rethink our impact on the planet. Adam Frank, an astrophysicist, explores the concept of planetary intelligence and the interconnectedness of life. Together, they highlight the necessity of transformative discussions and a shift in our understanding of intelligence, urging a more empathetic relationship with nature.

Mar 29, 2025 • 52min
Listening to Whales
Shane Gero, a marine biologist dedicated to understanding sperm whale communication through Project CETI, joins Carl Zimmer, a New York Times science reporter known for his insights into whale science, and Mere Takoko, an Indigenous ocean and climate conservationist advocating for whale personhood. They discuss groundbreaking AI technologies that decode whale vocalizations, the deep social bonds within sperm whale families, and Indigenous perspectives on giving these majestic creatures rights. This engaging conversation highlights the urgent need for conservation and understanding our connection to marine life.

Mar 22, 2025 • 52min
Deep Time: The Cosmos and Us
In this engaging discussion, theoretical physicist Marcelo Gleiser, poet Marjolijn van Heemstra, and physicist Carlo Rovelli explore the intricate tapestry of time and existence. They reflect on the personal and cosmic implications of time, sharing insights about the Big Bang and black holes. The conversation dives into the overview effect experienced by astronauts and how it alters perspectives on interconnectedness. They also tackle mortality's acceptance, emphasizing a serene approach to life and our vast universe.

Mar 15, 2025 • 52min
Jazz Migrations
Music crosses boundaries between traditional and modern, local and global, personal and political. Take jazz — a musical form born out of forced migration and enslavement. We typically think it originated in New Orleans and then spread around the world. But today, we examine an alternate history of jazz — one that starts in Africa, then crisscrosses the planet, following the movements of people and empires -- from colonial powers to grassroots revolutionaries to contemporary artists throughout the diaspora.This history of jazz is like the music itself: fluid and improvisatory. In this hour, produced in partnership with the Consortium of Humanities Centers and Institutes (CHCI) — a global consortium of 270 humanities centers and institutes — we hear how both African and African-American music have shaped the sound of the world today. Original Air Date: July 04, 2020Interviews In This Hour: How Meklit Hadero Reimagined Ethiopian Jazz — So You Say You Want A Revolution — Reclaiming the Hidden History of South African Jazz — 'We Are All African When We Listen'Guests: Meklit Hadero, Valmont Layne, Gwen Ansell, Ron RadanoFurther Reading:CHCI Ideas from Africa HubNever want to miss an episode? Subscribe to the podcast.Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.

Mar 8, 2025 • 52min
We Need to Talk About COVID
Join grief expert David Kessler, former Harvard president Drew Gilpin Faust, and funeral singer Lauren DePino as they delve deep into the emotional aftermath of COVID-19. They discuss the unspoken grief of lost connections and the societal impact of collective mourning. Faust shares insights from history, revealing lessons from the Civil War, while DePino highlights how funeral music can act as a balm for the grieving. Together, they explore the importance of embracing our losses to foster healing and connection.

Mar 1, 2025 • 52min
What is tribal sovereignty?
Most Americans take their sovereignty for granted — the nation’s right to make its own laws and govern its own people. The same rights we recognize in other sovereign nations, with one glaring exception — the Native nations and tribes who were here first. For Native Americans, sovereignty is not some abstract idea. It’s an ongoing, daily struggle. Original Air Date: July 13, 2024Interviews In This Hour: The battle over tribal rights in Bad River — Quannah ChasingHorse’s two worlds – Native activist and supermodel — Are Indian casinos the key to tribal sovereignty? — No more Native American 'trauma porn'Guests: Mary Mazzio, Quannah ChasingHorse, Steven Andrew Light, David TreuerNever want to miss an episode? Subscribe to the podcast.Want to hear more from us, including extended interviews and favorites from the archive? Subscribe to our newsletter.

Feb 22, 2025 • 52min
Being Body Conscious
Jessi Kneeland, author of "Body Neutral," discusses the shift from body positivity to neutrality, emphasizing acceptance over societal expectations. Rae Johnson, a somatic movement therapist, shares insights on "embodied activism," highlighting the connection between physical presence and social change. Sami Schalk, an associate professor and author, explores the intersection of Black disability politics, linking identity, disability, and empowerment. Together, they challenge traditional views of body image and advocate for a more inclusive understanding.

22 snips
Feb 15, 2025 • 52min
Deep Time: The Art of Time
Katie Paterson, an award-winning Scottish artist, talks about creating cosmic art that connects us with ancient times. Jonathon Keats, a conceptual artist, challenges traditional clocks by introducing alternatives like river time and bristlecone pine time. Acoustic ecologist Alex Braidwood shares his unique experience of recording dawn choruses and using them for community connection during the pandemic. Together, they explore how art, science, and nature intertwine to craft a deeper understanding of time, urging us to embrace 'timefulness' and reflect on our ecological footprint.
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