Knowledge is information that has causal power. It is not just a matter of belief or human psychology, but rather information that can cause physical effects. This definition of knowledge is derived from Karl Popper's idea of knowledge without a knowing subject. There are two main types of knowledge: scientific knowledge in human minds and knowledge in the form of adaptations in genes of living organisms. The latter type is not knowledge in a knowing subject, but it is information that is highly effective in causing physical effects. Humans, however, can transcend this type of knowledge in two ways. Firstly, the amount of information in human brains is significantly greater than in DNA. Secondly, humans possess explanatory knowledge and understanding, which has infinite reach and allows for achievements beyond the scope of biological evolution.