Knowledge is a powerful tool that should be actively utilized to combat suffering, pain, delusion, and desire. Instead of being passive and allowing external factors, referred to as the 'enemy', to affect emotional states, one must engage with this knowledge. Experiencing life's challenges is essential; rather than merely lamenting over struggles, one should test and apply the teachings learned. Observation of one's responses to hardship, such as physical pain, can deepen understanding and facilitate mastery over suffering, ultimately reducing both worldly and self-imposed distress.