Zachary Roberts
Physician-scientist and Chief Medical Officer at Allogene Therapeutics, specializing in immunology and CAR T-cell therapy development, and discussing Allogene's allogeneic CAR T Alpha-3 clinical trial.
Best podcasts with Zachary Roberts
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Nov 24, 2025 • 54min
A CAR T Revolution: Allogene is Bringing Lifesaving Cancer Treatment to More Patients
Dr. Zachary Roberts, Chief Medical Officer at Allogene Therapeutics and an expert in immunology, sheds light on the revolutionary potential of allogeneic CAR T-cell therapy. He discusses the triumphs of CAR T in treating blood cancers and the daunting barrier of patient access, with only 20% receiving treatment. Roberts unveils how 'off-the-shelf' therapies, using donor T-cells, promise to bypass manufacturing hurdles. He also highlights the innovative Alpha-3 trial, aiming to treat high-risk patients earlier for better outcomes.
Aug 29, 2024 • 25min
Scaling Allo with Allogene Therapeutics' Dr. Zachary Roberts
Dr. Zachary Roberts, EVP of R&D and CMO at Allogene Therapeutics, dives into the complexities of chronic lymphocytic leukemia (CLL) and critiques existing CAR T therapies. He emphasizes why allogeneic approaches may offer a scalable and effective solution. The conversation highlights the advantages of allogeneic cell therapies, their impact on treatment accessibility, and the promising Phase Two Alpha-3 trial. Furthermore, Dr. Roberts discusses novel advancements in CAR T therapies and their potential applications in treating both cancer and autoimmune diseases.
