Evgenia Abbruzzese, co-founder of the Society for Evidence-Based Gender Medicine, shares insights on diagnostic definitions and the historical context of gender dysphoria. Farr Curlin, a physician and bioethicist, discusses the ethical implications of treatment options. Yuan Zhang elaborates on the rigorous evidence evaluation methods used in the HHS report. Christopher Kaliebe outlines clinical practices for treating youth with gender dysphoria, while philosopher Alex Byre critiques the language surrounding gender identity. Together, they uncover the complexities and uncertain outcomes of current pediatric gender treatments.