
Wolfgang Clough
Researcher at Mercy Hospital discussing the MET gene
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Sep 11, 2023 • 3min
Updates: MET Targeted Therapy for EXON 14 Mutations in Lung Cancer
Researchers discuss MET gene alterations in lung cancer, focusing on targetable changes like exon 14 skipping mutations and fusions. Capmatinib and Crizotinib show promise as treatments, but drug resistance remains a challenge. Various MET tyrosine kinase inhibitors are in development or under evaluation for potential combination therapies.