William Pao
Oncologist and drug researcher and author of Breakthrough – The Quest for Life-Changing Medicines, discussing the science and process behind developing new drugs.
Best podcasts with William Pao
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Jun 11, 2025 • 1h 17min
Breakthrough: The stories behind Life-Changing Therapies | Dr. William Pao former CDO of Pfizer
Dr. William Pao, CEO and co-founder of Revelio Therapeutics, shares his compelling journey from losing his father to colon cancer at 13 to spearheading breakthroughs in lung cancer research. He discusses the discovery of EGFR mutations and the fierce competition in publishing this pivotal finding. Dr. Pao highlights the serendipitous origins of Tylenol and delves into drug development challenges in the biotech world. He offers valuable insights on resilience for aspiring entrepreneurs and the future of medical innovation.
Sep 28, 2025 • 34min
Inside the hunt for life-changing medicines
Dr. William Pao, an oncologist and drug researcher, dives into the intricate journey of drug development in his insightful discussion. He reveals the astonishingly low approval rates of new drugs and explains the collaborative nature of research that spans decades. Pao underscores the significance of basic science in breakthroughs and shares the fascinating story of paracetamol's accidental discovery. He also discusses the challenges of clinical trials and the variability in patient responses, offering a glimpse into future advancements in medicine.
