Jeff Carr, Science editor for The Economist, and Wendelin von Bredow, Business writer for The Economist, dive into the alarming emergence of more transmissible coronavirus variants from Britain and South Africa. They discuss the implications for vaccine efficacy and public health strategies. The conversation shifts to a significant lawsuit against Walmart over its role in the opioid crisis, exploring legal ramifications and corporate responsibility. They also touch on the challenges of unused vacation days stemming from the pandemic's toll on work-life balance.

Ben Farmer, a keen observer of Afghanistan's evolving landscape, speaks with Wendelin von Bredow, The Economist's European finance expert. They dive into the budding peace talks between the Afghan government and the Taliban, revealing the challenges of a potential prisoner swap and the looming fears over rights erosion. Transitioning to Europe, the duo uncovers the shocking Wirecard scandal, detailing the complexities of fraud in the financial sector. They also explore how African football triumphs can unify nations amid conflict, revealing sport's power in societal healing.

John Prideaux, an expert on Brexit and international trade, and Wendelin von Bredow, the European business correspondent for The Economist, discuss the current state of post-Brexit trade negotiations. They outline the tough challenges negotiators face, including the looming threat of a no-deal scenario. The conversation also shifts to innovative uses of digital twin technology in healthcare for heart monitoring. Additionally, they delve into the complex legal case surrounding the Rothschild Foundation, highlighting historical injustices faced by the family.

Brooke Unger, America's editor for The Economist, shares her expertise on the Chilean protests that evolved from fare hikes into a powerful movement for social equality. Wendelin von Bredow, European business and finance correspondent, discusses the economic successes and political challenges facing the Visegrad Four countries. The conversation highlights systemic inequalities in Chile and examines labor market dynamics in Central Europe, raising questions about the future of democracy and economic stability.

Nick Pelham, The Economist's Middle East correspondent, sheds light on the Kurdish resurgence in northeastern Syria, revealing their transition from oppression to autonomy. He discusses the cultural revival amid complex power dynamics with local Arabs. Meanwhile, Wendelin von Bredow dives into the ramifications of the murder of German politician Walter Lübcke, painting a stark picture of rising far-right extremism and its implications for democracy. The podcast also touches on surprising developments in China's education system where students adopt American-style debate techniques.