Dr. Wallace J. Brownlee, a renowned neurologist specializing in multiple sclerosis from Queen Square MS Centre, dives into the evolving landscape of MS diagnosis. He discusses the diminishing focus on dissemination in time (DIT) when high dissemination in space (DIS) criteria are met. The conversation also covers advanced diagnostic techniques like MRI and cerebrospinal fluid analysis. Brownlee outlines the significance of detecting lesions and emphasizes the role of optic neuritis in refining current guidelines for diagnosing relapsing remitting MS.