Vijay Sankaran

Physician-scientist specializing in hematology research with expertise in genetic and mechanistic studies of acute myeloid leukemia, contributing work on MECOM repression and CEBPA regulation.

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Dec 18, 2025 • 20min

Novel Differentiation Therapies for AML and Prognostic Value of PET in MM

Vijay Sankaran, a physician-scientist in hematology research, Ruud Delwel, a leukemia biology expert, and Françoise Kraeber-Bodere, a nuclear medicine physician, delve into groundbreaking studies on the MECOM gene's impact on acute myeloid leukemia therapies. They explore how MECOM repression might enhance CEBPA expression to promote differentiation in leukemias. Also discussed are the promising results from the CASSIOPET study showing that pre-maintenance PET negativity is a strong prognostic indicator for multiple myeloma outcomes.

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