Dr. Vasisht Srinivasan, an Emergency Medicine physician and neurointensivist at the University of Washington, discusses a critical case of a patient with a suspected intracerebral hemorrhage. He delves into the management of hemorrhagic strokes, highlighting the role of reversing Factor Xa inhibitors like Andexanet. The conversation touches on the efficacy and ethical implications of recent clinical trials, revealing concerns about potential conflicts of interest and thrombotic events. Ultimately, it emphasizes the balance between emerging treatments and patient outcomes.

Dr. Vasisht Srinivasan, an Emergency Medicine physician and neurointensivist at the University of Washington, dives into the complexities of treating acute ischemic strokes. He discusses a compelling case of a 70-year-old woman and evaluates the shift from alteplase to tenecteplase (TNK) in treatment. The conversation highlights advancements in thrombectomy trials and scrutinizes conflicts of interest in clinical studies. Potential safety concerns and the importance of shared decision-making in stroke treatment underscore the need for ongoing research and adherence to established guidelines.