Join Professor Sir Stephen Holgate, an expert in allergy and lung diseases, and Tom Whipple, science editor at The Times, as they tackle the alarming rise in food allergies in the UK. They discuss the staggering increase in hospitalizations due to anaphylaxis and what's driving this trend. The conversation dives into the significance of genetics and environmental factors, the role of everyday microbes, and innovative approaches like immunotherapy. Personal stories add depth, showcasing the urgent need for research and awareness in combating this public health crisis.

Ever since the discovery of DNA scientists have been on a quest to understand the secrets of the human genome. This quest has not only involved analysing the role genes play in making us who we are – the history of genetics has also been shaped by a desire to explore how far our genes can be altered or enhanced. In 2012, the discovery that a tool known as CRISPR could be programmed to add and remove elements of DNA marked a huge leap forward, transforming research into treatments for diseases as varied as cancer, Alzheimer’s, sickle cell and HIV, as well as many rare genetic conditions. In this conversation, recorded at the Francis Crick Institute in London, our panel explores the urgent ethical questions that these advances have unleashed. Chaired by Dr Guddi Singh, the panel featured Tom Whipple, Science Editor at The Times, Shani Dhanda, an award-winning disability activist and inclusion specialist, Dr Güneş Taylor, postdoctoral research scientist at the Francis Crick Institute, and Jimi Olaghere, one of the first people in the world to take part in a life-changing clinical trial using gene therapy to treat sickle cell disease. In this episode (Part I) the panel explores questions such as: what diseases should we try to cure? How should these be prioritised? What assumptions shape perceptions of disability? Where does the line between editing and enhancing fall? And ultimately who gets to decide? The event was organised to coincide with a free exhibition at the Francis Crick Institute, London called ‘Cut + Paste,’ exploring the future and ethics of gene editing. The exhibition runs until December 2023. Visit www.crick.ac.uk/CutandPaste to find out more.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Tom Whipple, the Science Editor at The Times, dives into the intriguing world of pulchronomics—the economics of beauty. He discusses how physical attractiveness impacts both love lives and career paths, revealing that our fortunes can indeed be swayed by looks. Whipple examines historical studies linking beauty to economic mobility, and the societal biases that affect perceptions of attractiveness from a young age. The conversation also critiques our changing standards around beauty and the emotional toll on those considered 'unattractive,' showcasing a broader narrative on self-perception.

Tom Whipple, Science Editor at The Times, discusses the growing belief in animal consciousness, exploring emotions in animals, the historical rejection of this idea, and the implications of recognizing it. The podcast delves into behaviors indicating consciousness in animals, such as play and self-recognition, challenging human assumptions about animal awareness and moral implications.

Health chiefs have declared a national incident following a surge in measles cases. The tragic story of Rold Dahl's daughter highlights the importance of vaccinations. Andrew Wakefield's controversial anti-vaxx career and film is discussed. Addressing anti-vaccine sentiments and cultural concerns, as well as exploring the surge in measles cases, are also covered in the episode.