Join Boris Heifets, a Stanford anesthesiologist researching psychedelic medicine, and Theresa Lii, his collaborator in exploring ketamine and the placebo effect. They dive into the surprising dynamics of ketamine in depression treatment. Discover how much of its efficacy stems from the drug versus the excitement of trial participation. They also discuss the complex interplay between the placebo effect and the opioid system, while challenging conventional views on placebo in psychiatric care, revealing its potential as a valuable aspect of treatment.