Arturo Casadevall, a leading scientist on fungal species, and journalist Stephanie Desmon discuss the fascinating world of fungi and their critical role in ecosystems. They explore the dual nature of fungi as both lifesavers and killers, highlighting the urgent need for better treatments for fungal infections. The conversation includes innovative research at Johns Hopkins, focusing on the resilience of fungi in changing climates and their implications for public health and food security. Get ready to rethink our relationship with these incredible organisms!