Dr. Scott Richardson, an expert in differential diagnosis, teams up with Dr. Gordon Guyatt, a pioneer in medical decision-making. They explore the critical role of disease probability in clinical settings, emphasizing evidence-based practices. The conversation dives into effective strategies for diagnosing chronic cough, dissecting common and rare causes. They also evaluate the trustworthiness of medical studies and discuss how enhanced electronic health records can optimize patient care. A thought-provoking episode full of insights for better diagnostic accuracy!