Guests Steve Witkoff, Trump's former top negotiator, discusses the complexities of Middle East peace talks and the delicate balance in Israel-Hamas negotiations. Former FDA commissioner Scott Gottlieb highlights the urgent public health crises, focusing on alarming measles outbreaks and the need to combat vaccine misinformation. They dive into the repercussions of workforce cuts in health agencies and how these changes could affect American health oversight moving forward. Expect a thought-provoking discussion on governance, health, and international diplomacy.

Scott Gottlieb, former FDA commissioner and healthcare expert, and Patrick Boyle, financial commentator and YouTuber, dive into pressing topics. They explore the political implications of vaccine announcements and transparency issues with big pharma, specifically Pfizer. The conversation shifts to the fintech landscape, discussing the risks of debanking practices and regulatory scrutiny. Gottlieb and Boyle also touch on the geopolitical landscape, with insights into the Ukraine conflict and its broader implications for international relations.

Scott Gottlieb, former head of the FDA and author of 'Uncontrolled Spread,' dives into the lessons learned from the COVID-19 pandemic. He discusses the critical role technology, particularly mRNA vaccine development, played in pandemic response and highlights failures in regulatory translation of science to policy. Joining him are Marc Andreessen, a prominent venture capitalist, and Vineeta Agarwala, a bio expert. They explore the need for improved genomic surveillance, private sector involvement in health infrastructure, and the ethical dilemmas of challenge trials for future preparedness.

Dr. Scott Gottlieb, former FDA commissioner and Pfizer board member, breaks down the complexities of UnitedHealth's Medicare billing amid a DOJ investigation. He discusses healthcare system inefficiencies and the potential impact of bird flu cases. Meanwhile, Brian Armstrong, Coinbase's CEO, shares exciting news about the SEC dropping its lawsuit, emphasizing the need for clear regulations in cryptocurrency. He also touches on meme coins and prediction markets, illuminating the evolving landscape of digital finance.

Amos Hochstein, a former Biden senior advisor, shares insights on the fragile ceasefire in the Israel-Hamas conflict and the urgent humanitarian needs. Dr. Scott Gottlieb, former FDA commissioner, examines the alarming potential impacts of proposed NIH funding cuts on public health research. The conversation also touches on Elon Musk's ambitious $97.4 billion bid for OpenAI and tensions with CEO Sam Altman, and President Trump's pause on anti-bribery law enforcement, raising ethical concerns in international business.

Steve Liesman, a CNBC reporter specializing in economic analysis, discusses the implications of President Trump's tariffs on Canada and Mexico. Former FDA Commissioner Dr. Scott Gottlieb critiques Robert F. Kennedy Jr.'s understanding of healthcare during his challenging confirmation hearings. Mellody Hobson, co-CEO of Ariel Investments, speaks about the exciting investment landscape in women’s sports, particularly with the new National Women’s Soccer League franchise in Denver, advocating for diversity and inclusion in corporate leadership.

Scott Gottlieb, former FDA commissioner, dives into the alarming rise of flu, RSV, and norovirus this winter, shedding light on why these illnesses are peaking. He discusses the strain on healthcare systems and the crucial role of public health policies. Additionally, the conversation touches on major executive changes at Apple and Disney, probing into how these leadership shifts might shape the future of these giants in 2025. The complexities of healthcare challenges and their implications for society also take center stage.

Joining the discussion is Scott Gottlieb, former FDA commissioner and current CNBC contributor, who shares insights on the shifting landscape of U.S. healthcare, particularly under potential political changes. Gary Vaynerchuk highlights the booming trend of live shopping on TikTok, where influencers are cashing in like never before, echoing the QVC model. The conversation also touches on the FTC's investigation into Microsoft, philanthropy’s effects on the wealthiest Americans, and the rising films that made waves this Thanksgiving.

Dr. Scott Gottlieb, former FDA Commissioner, provides critical insights on public health, highlighting the rising threat of mosquito-borne viruses and the need for improved safety regulations in medical labs. He emphasizes the importance of pandemic preparedness to prevent future outbreaks. The discussion also touches on generational travel trends and tips for fall vacations, advocating for exploring lesser-known destinations. Overall, it's a thought-provoking blend of travel advice and health safety in a changing world.

Join Richard Haass, President Emeritus of the Council on Foreign Relations, and Dr. Scott Gottlieb, former FDA Commissioner, as they tackle pressing global issues. Haass discusses escalating Middle East tensions and the impact of U.S. support on geopolitics. Meanwhile, Gottlieb dives into the fentanyl crisis, revealing its devastating toll on American lives and advocating for tougher measures against its trade. The conversation also touches on the implications of these issues for the upcoming U.S. elections and recent alarming security concerns.