Nicole Byer celebrates episode 300 with her best friend, Sasheer Zamata. They discuss Nicole's dating life, favorite dates, best dating advice, and new favorite sex toys. They also answer listener questions about cheating, dating someone with a bad social media persona, and Tinx's Box Theory.

Sasheer Zamata, known for her role in Marvel's Agatha All Along, joins the conversation to dive into the quirky debate over shoe covers for guests. They explore the societal anxieties tied to our feet—are they truly the most stigmatized body part? The discussion touches on the absurdity of social etiquette surrounding footwear in homes, mixing humor with relatable anecdotes. With a candid reflection on celebrity culture's influence, this chat challenges listeners to rethink comfort and cleanliness in social settings.

Join Sasheer Zamata, a talented comedian known for sketch comedy, as she shares her Marvel debut experience in a Disney+ series and her preparations for singing with Broadway's Patti LuPone. Michael Kosta teams up with Jordan Klepper to explore the hilarious chaos of Taylor Swift's political impact and the surprising friendships across party lines. John Leguizamo dives into alarming tactics against Latino voting rights, combining insightful commentary with comedic flair. It's a delightful mix of politics, humor, and pop culture!

Tom Ellis and Sasheer Zamata discuss the Netflix animated series based on Exploding Kittens, where God and the devil take the form of talking cats. They delve into the show's world-building and fresh perspective, highlighting comedic moments and character dynamics. The hosts share varied reactions to the adaptation, praising the voice acting and discussing fan opinions and anticipation for season two.

Leslye Headland and Sasheer Zamata join to discuss the 1983 movie Hercules, mocking its robots, Hercules throwing a bear into space, Lou Ferrigno’s voice, and more absurdities. They joke about the movie's dubbing, bizarre scenes, and cheap production quality, providing humorous critiques throughout.