Chandra Reynolds is a seasoned expert in aging and sedentary behavior, while Ryan Bruellman is a PhD candidate specializing in genetics and health outcomes. They discuss alarming findings linking over 8.5 hours of daily sitting to increased BMI and cholesterol levels. The conversation highlights the comparison of sitting risks to smoking and suggests that just 30 minutes of vigorous exercise can significantly mitigate these health risks. They also emphasize the importance of incorporating movement into daily routines to combat the sedentary epidemic.