Dr. Peta Alexander, a Senior Associate Cardiologist and ECMO Program Director at Boston Children’s Hospital, and Dr. Ryan Barbaro, Service Chief of Pediatric Critical Care Medicine at C.S. Mott Children's Hospital, delve into the intricacies of pediatric ECMO. They discuss the critical differences between pediatric and adult eCPR, challenges in supply chain management, and the urgent need for standardized practices. Their dialogue highlights collaborative efforts in defining ECMO-associated complications and the promise of ongoing research to enhance pediatric care.