Dr. Rupinder Sahsi, an emergency physician and EBM enthusiast with academic ties to McMaster and Wright State universities, joins to discuss the safety of nitroglycerin use in right ventricular myocardial infarctions (RVMI). The conversation delves into the historical doubts surrounding nitrates and highlights a recent meta-analysis that suggests reassessing prior clinical guidelines. Dr. Sahsi critiques existing studies and calls for a more evidence-based approach, balancing clinical insights with anecdotes that keep the discussion lively.