Laura Murphy, Director of Education and Awareness at the International Association for Premenstrual Disorders, and Rosie Worsley, Melbourne-based endocrinologist, delve into the complexities of PMDD. Laura shares her personal battles with the disorder, revealing how PMS can morph into debilitating depression. They discuss the misdiagnosis of PMDD, the hormonal influences on emotions, and the urgent need for better awareness. Clinical trials for treatments are also highlighted, as well as the challenges women face in navigating treatment options.