Ann Arvin, professor emerita at Stanford Medical School, and Robert Johnson, a physician and researcher at the University of Bristol, delve into the perplexing link between chickenpox and shingles. They recount a riveting detective story from the 1950s that clarified this connection. Arvin emphasizes the importance of vaccination in preventing severe outcomes, while Johnson shares his insights on treating long-term pain caused by shingles. Together, they explore the complexities of shingles, its symptoms, and the biopsychosocial approach to pain management.