Robert Boyd, an anthropologist known for the Dual-Inheritance Theory, and Peter Richerson, an expert at the crossroads of culture and genetics, delve into how culture has shaped human evolution. They discuss the significant role of tool use among early hominins in cognitive development. The duo highlights how cultural practices influenced genetic evolution, especially in farming and urban transitions. They also explore the unexpected effects of climate on brain size and the implications of cultural dynamics in modern communities, sparking a fascinating dialogue on human adaptability.