Gregory Curfman, Executive Editor at JAMA, and Robert O. Bonow, JAMA Cardiology Editor, tackle pressing advancements in cardiac care. They discuss the benefits of remote ECG monitoring for atrial fibrillation detection and the safety of discontinuing anticoagulants post-ablation. The duo also dives into the comparative effectiveness of semaglutide and tirzepatide in heart failure treatment. Lastly, they underscore the significance of bivalent RSV vaccination for older adults, while highlighting the need for greater female representation in cardiovascular trials.