Rob Russo, The Economist's Canada correspondent, reveals the internal party conflicts leading to Justin Trudeau's resignation and the implications for future Canadian elections. Sophie Pedder, Paris bureau chief, reflects on the legacy of the Charlie Hebdo attacks, emphasizing the publication's commitment to satire despite ongoing threats. The discussion also highlights AI's transformative potential in the pharmaceutical industry, focusing on how it could reshape drug development by 2025, amidst challenges and optimism for future innovations.

Rob Russo, The Economist's Canada correspondent, delves into the resignation of Prime Minister Justin Trudeau, discussing the internal pressures and shifting political landscape that led to his exit. He highlights the potential successors and the impact on Canada's future. Meanwhile, Sophie Pedder reflects on the resilience of Charlie Hebdo ten years after the tragic attack, exploring themes of freedom of expression and the ongoing challenges faced by the publication. The conversation also touches on the intersection of AI and pharmaceutical development, offering insights into its transformative potential.

Rob Russo, Canada correspondent for The Economist, and Stephanie Levitz from the Globe and Mail discuss Canada's response to Trump's tariff threats and the complexities of U.S.-Canada relations. Historian Evan Friss delves into the enduring charm of independent bookstores, highlighting their community significance amidst technological challenges. Carolyn Weitzman tackles Canada’s housing crisis and explores effective solutions, while the show wraps up with a light-hearted puzzling challenge that sparks engagement and fun.