Rick Johnson, a Professor of Nephrology at the University of Colorado, dives deep into the surprising effects of fructose on metabolic health. He reveals how fructose metabolizes differently than glucose, contributing to weight gain and insulin resistance. Johnson explains the alarming connection between fructose and high blood pressure, as well as its link to conditions like fatty liver and diabetes. He also shares insights on uric acid levels and the potential benefits of fructokinase inhibitors, challenging common beliefs about sugar and artificial sweeteners.

Rick Johnson, Professor of Nephrology at the University of Colorado, dives into the intriguing world of fructose metabolism and its ties to metabolic diseases. He explains how our ancestors’ survival mechanisms now pose health risks, revealing how glucose can convert to fructose. The conversation highlights the significant decline in metabolic flexibility with age, the impacts of sugar and dietary habits on our health, and strategies for preventing metabolic illnesses, including dietary modifications and innovative pharmaceutical approaches.

Rick Johnson, a nephrology professor at the University of Colorado, delves into the metabolic effects of fructose on health. He reveals how fructose ties into blood pressure regulation and discusses its impact on insulin resistance and obesity. Johnson contrasts glucose and fructose, shares insights on uric acid's role in health, and explores the implications of fructose in modern diets. Artificial sweeteners vs. real sugar also come under scrutiny, alongside innovative pharmacotherapy strategies for treating related health issues.