Dr. Sunandana Chandra, a medical oncologist and director of melanoma care at Northwestern, joins Dr. Riad Salem, an interventional oncologist specializing in metastatic melanoma treatments. They discuss the evolution of melanoma management, highlighting innovative approaches like immunotherapy and intratumoral oncolytic viruses. The conversation dives into key clinical trials, including IGNYTE-3, and best practices for administering therapies. Their collaborative approach showcases the importance of multidisciplinary teams in enhancing patient-centered care and improving outcomes in advanced melanoma.