In this discussion, Karl Friston, a pioneering neuroscientist, and Anna Lembke, a leading expert in addiction, explore the urgent need for societal change amidst crises in mental health and addiction. They delve into the concept of active inference and its relevance to personal narratives and decision-making. Tech insights from Raphael Kaufman and Bert DeVries enrich the conversation, while Guillaume DeMa emphasizes implications for mental health. Together, they challenge listeners to rethink consciousness and mental health in our fast-evolving, tech-driven world.