Prof. Hazel Everitt, a GP and lead author on a significant study regarding amitriptyline for IBS, joins the discussion. She shares insights into how low-dose amitriptyline can effectively manage IBS symptoms. The conversation also dives into the controversial use of methotrexate for hand osteoarthritis, revealing the complexities of pain management. Additionally, they explore a patient information leaflet aimed at alleviating lower urinary tract symptoms and whether such resources can be more beneficial than traditional medications. Empowering patients remains a key focus.