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Prem Kandiah
Neurointensivist and transplant/liver intensivist with expertise in ammonia, hyperammonemia, and encephalopathy; invited as the episode's subject-matter expert on ammonia physiology and management.
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Dec 24, 2025
• 56min
Episode 96: Understanding ammonia, with Prem Kandiah
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Dr. Prem Kandiah, a neurointensivist and ammonia expert, dives deep into the complexities of ammonia physiology and its critical care implications. The discussion highlights the unique ways ammonia can affect the brain, including mechanisms of injury and the importance of timely measurement. Kandiah explores less-known causes of hyperammonemia, such as urease-producing infections and malnutrition, especially in post-bariatric patients. He also offers practical tips for accurate ammonia testing and discusses acute management strategies.
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