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Paul Zarkowski
Psychiatrist and researcher who analyzed STAR*D trial data to study SSRI side-effect trajectories, offering evidence-based insights on antidepressant tolerability.
Best podcasts with Paul Zarkowski
Ranked by the Snipd community
Nov 27, 2025
• 11min
Do SSRI Side Effects Improve Over Time?
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Dr. Paul Zarkowski, a psychiatrist and researcher known for his analysis of the STAR*D trial data, dives into the controversial belief surrounding SSRI side effects. He discusses whether these effects truly diminish over time, revealing that some patients may actually face worsening symptoms. Zarkowski explains concepts like survivor bias and presents data showing distinct side-effect trajectories. He also highlights persistent problems such as sexual and sleep-related side effects and stresses the importance of early assessments for effective patient counseling.
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