Dr. Paul Marino, a critical care specialist and author of the bestselling "The ICU Book," dives into the multifaceted role of oxygen in medicine. He challenges widely held beliefs about oxygen delivery, probing its dual nature as an energy booster and potential threat. The discussion includes the dynamics of hemoglobin in oxygen transport, the complexities of oxygen in athletic performance, and the fascinating story of climbing Everest without supplemental oxygen. Marino advocates for a reevaluation of oxygen therapy and highlights its physiological intricacies.