
Paul A. Spagnuolo
Researcher at the University of Guelph
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Jan 16, 2024 • 2min
Reductive Carboxylation of Glutamine as a Potential Target in AML
Researcher guests Alessia Roma, Lawrence D. Goodridge, and Paul A. Spagnuolo from the University of Guelph discuss the aggressive nature of acute myeloid leukemia (AML) and the potential of reductive carboxylation of glutamine as a target for novel therapies to improve patient outcomes. They highlight the importance of understanding metabolic vulnerabilities in AML and the advancements in targeting these vulnerabilities in drug development.