Patricia Arquette, an Academy Award-winning actress known for her gripping roles, discusses her character Harmony Cobel and how her Newfoundland roots shaped Cobel’s complex persona. Comedian Jimmy Kimmel joins the conversation, answering quirky listener questions and reflecting on nostalgic anecdotes from their careers. The trio dives into the unique filming dynamics, creative choices in storytelling, and the whimsical nature of their experiences, blending humor with heartfelt connections in the entertainment world.