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Paolo Springhetti
Cardiologist and researcher from Milan with expertise in transcatheter valve therapies and clinical trial interpretation, invited to discuss the LANDMARK trial findings.
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Nov 24, 2025
• 7min
Journal editorial - The emerging story of Myval transcatheter heart valve: lessons from the LANDMARK trial
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Paolo Springhetti, a Milanese cardiologist specializing in transcatheter valve therapies, joins Marie-Annick Clavel to discuss the LANDMARK trial findings. They dive into the unique sizing advantages of Myval compared to competitors, highlighting impressive hemodynamic outcomes. Sex-specific definitions of patient-prosthesis mismatch (PPM) come under scrutiny, revealing stark differences among valve types. The duo also explores the implications of Myval's low-flow recovery and durability concerns for younger patients, emphasizing the need for long-term studies.
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