Conan chats with Pam, a former Poison Control employee, about handling calls on accidental ingestions and overdoses. They discuss childhood memories, mushrooms, and edible marijuana experiences, all with a comedic tone. The episode also covers versatile pants, a Miller Lite beer ad, and a comical Disneyland incident involving cannabis edibles. The conversation ends with playful banter and gratitude.

Pam, an expert in booking premium flights, shares her Abu Dhabi journey flying Etihad's luxury apartments using credit card points. From the excitement of securing a deal to the exquisite dining experience onboard, she paints a vivid picture of luxury travel. Embracing spontaneity, she explores the joy of experiencing world-class comfort in the skies, turning a simple flight booking into an unforgettable adventure.

Rick Banks, alongside Rich and Pam, critically analyzes the impact of Brown v. Board of Education on American education, discussing the slow progress in desegregation and exploring alternative approaches to achieve racial and socioeconomic integration in schools.

For a special Mother's Day episode, Eve and Pam join the guys. Topics include moms sharing notes, helping a caller with a butterfly fear, assisting a golfer, and following up with a previous caller. The episode offers humor, heartwarming moments, and quirky advice to tackle fears and pranks involving deer.

Chloé, Meg, and Pam explore motherhood in Harry Potter, discussing Merope Gaunt's sacrifice, Narcissa's role, and the evolving role of women in the fandom. They reflect on the characters' maternal qualities, such as Hermione's friendship with Harry, and how even characters like Umbridge represent motherhood in their own ways.