
Omkar Desai
Research perspective co-author from the Department of Surgery at Case Western Reserve University and University Hospitals Cleveland Medical Center
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Oct 12, 2023 • 9min
HER3: A Vital Target in Cancer Treatment
Dr. Omkar Desai discusses the significance of HER3 in promoting cancer cell growth and chemo resistance. Challenges in translating preclinical studies on HER3 targeted therapies to clinical trials and HER3 overactivation as a resistance mechanism in cancer cells are explored. Emphasizing the importance of identifying HER3 expression and gene fusions as predictive biomarkers and developing combination therapies to combat resistance.