In this engaging discussion, Nirdosh Ashok Kumar, an Emergency Medicine Specialist from Aga Khan University Hospital in Karachi, dives into the complexities of diagnosing Acute Aortic Syndrome (AAS). He highlights the high misdiagnosis rates and the importance of timely intervention. The conversation sheds light on various biases in AAS research and the challenges of clinical decision-making amid limited resources. Kumar emphasizes the need for better communication with patients to enhance understanding of symptoms, ultimately aiming to improve outcomes in emergency settings.