Nikos Koundouros

Postdoctoral fellow in John Blenis’ lab at the Meyer Cancer Center at Weill Cornell Medicine. His research interests include understanding the fundamentals of nutrient sensing in breast cancer.

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May 15, 2025 • 1h 47min

Linoleic Acid, Seed Oils, mTOR & Breast Cancer | Nikos Koundouros & John Blenis | 229

Nikos Koundouros, a postdoctoral fellow at Weill Cornell Medicine, joins John Blenis, a prominent pharmacology professor, to unravel how omega-6 fatty acids like linoleic acid may drive triple-negative breast cancer by activating the mTOR pathway. They discuss the critical role of the FABP5 protein, uniquely enhancing cancer cell sensitivity to these fats. The conversation reveals alarming shifts in modern diets, emphasizing the need for tailored nutrition approaches based on genetic variations and cancer subtypes to improve health outcomes.

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