Dr. Neha Dangayach, a neurocritical care physician at Mount Sinai, dives deep into neuroprognostication after cardiac arrest. She highlights the evolution of prognosis methodologies, emphasizing the importance of multimodal testing beyond a single exam. Uncertainty in outcomes is addressed, stressing shared decision-making to avoid premature life support withdrawal. Dr. Dangayach also discusses influential factors like arrest history, temperature, and biomarkers, urging a cautious approach to brain death declarations and the necessity for ongoing assessments post-arrest.