Nate Wienert, the creator of Tamagui and One Stack, simplifies complex development processes for universal apps with React Native. He discusses the journey of building Tamagui, its integration at Uniswap, and the advantages of a monorepo. Nate dives into challenges surrounding the VXRN library, debating Metro vs. Vite, and explores innovative solutions in data synchronization with a new approach called Zero. He also sheds light on merging React and React Native through a novel meta framework, enhancing user experiences across platforms.