Dr. Naomi O'Grady, a critical care and infectious disease physician at the National Institutes of Health, discusses Central Line-Associated Bloodstream Infections (CLABSI). The podcast covers the impact of CLABSI on patient outcomes, the definitions and pathophysiology of CLABSI and CRBSI, catheter contamination and prevention strategies, the importance of hand hygiene before sterile glove insertion, the use of chlorhexidine dressings to reduce CLABSI rates, and improving the healthcare system and emphasizing self-care.