Craig Garthwaite, a healthcare economics expert, Amanda Starc, who specializes in healthcare analytics, David Dranove, a health services authority, and Murray Ross from Kaiser Permanente discuss the American healthcare system’s misaligned incentives. They delve into the challenges patients face and share personal stories illustrating systemic failures. The conversation includes comparisons with Italy's healthcare model, the potential of preventive care, and the evolving roles of major companies like Amazon in the landscape, pushing for a collaborative approach to reform.