Mukund Raguram, a fourth-year medical student at UCSF and co-host of Space Learning, teams up with Jasdeep Bajwa, an academic hospitalist passionate about clinical reasoning. They dive into a complex case of a 65-year-old male with a severe chronic cough and a TB history. The discussion covers the systematic approach needed for accurate diagnosis, examining potential complications from previous TB, and the impact of endemic diseases. They also tackle the intricacies of testing for tuberculosis, emphasizing the importance of thorough clinical reasoning in patient care.