Miryam Naddaf, a reporter for Nature, dives into the exciting scientific landscape of 2025. She highlights upcoming lunar missions aimed at mapping resources on the Moon, crucial for climate science. The discussion touches on the impact of political changes, especially regarding climate commitments, and how they might shape scientific innovation. Naddaf also explores advancements in drug treatments and breakthrough physics projects, like CERN’s potential circular collider, which could redefine healthcare and exploration.