Charles Daley, a leading expert on mycobacterial diseases, Minh-Vu Nguyen, an infectious disease specialist, and Reeti Khare, director of a rare disease lab, dive deep into non-tuberculous mycobacterial pulmonary disease. They discuss the rising incidence of NTM infections, the challenges of accurate diagnosis, and the complexities of mixed infections. Insights on tailored treatment strategies, including the fight against macrolide resistance and new advancements in therapy, provide a hopeful outlook for patient care. Tune in for expert anecdotes and essential monitoring strategies!