Exploring anesthesia for TAAA repair with Dr. Mimi Wynn, focusing on preoperative concerns, intraoperative management, and reducing spinal cord ischemia risk. Discussing advancements in thoracic abdominal aortic surgery, strategies to minimize spinal cord injury, challenges in managing spinal drains in elderly patients, and neuroprotective strategies in vascular surgery. Exploring the evolution of approaches to reduce spinal cord ischemia risk, emphasizing physiologic strategies and validated therapies.