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Mike Blue
CEO of HistoSonics, the company developing histotripsy — an ultrasound-based technology that destroys tissue and tumors; appeared to discuss the device's development, clinical trials, and commercialization.
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Nov 13, 2025
• 34min
Using Sound Waves to Destroy Tumors
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Mike Blue, CEO of HistoSonics, shares his fascinating journey from a garage-built ultrasound prototype to an FDA-approved cancer treatment device. He discusses how converging sound waves create bubble clouds that destroy tumors non-invasively. After a setback with a failed clinical trial, he rebranded the technology and attracted funding. Blue also reveals insights from the pivotal HOPE for Liver trial, showcasing impressive results and patient outcomes, while addressing challenges in scaling their innovative treatment for various cancers.
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