Melody C. Carter, a leading researcher at NIH, shares pivotal insights into the genetic variant KIT M541L and its connection to mastocytosis. This variant may significantly influence the severity of the disease, which leads to an overproduction of mast cells in the body. Carter discusses the implications of this research on understanding mastocytosis and highlights how it could pave the way for personalized treatments. Tune in to learn about the fascinating intersection of genetics and immune disorders!